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Coach trips from Santiago to La Serena

from £5.99

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Bus stations and stops in Santiago

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Frequently asked questions

Fares for the journey between Santiago and La Serena start from £5.99. To get the best value on FlixBus tickets, consider travelling during off-peak hours and on weekdays. You can secure your ticket through this website or via the FlixBus app. We offer a variety of secure payment options, including card payments, PayPal, and Google Pay. Should you encounter any issues with payment, our payment help page is here to assist. Tickets can also be purchased onboard or at our selling points using cash.
With FlixBus, you can conveniently reach 2 destinations from La Serena, including Santiago, Viña del Mar, Valparaíso.
Yes, night trip options are available from Santiago to La Serena. Check out the route's schedule and choose the best option to suit your plans!
The route between Santiago and La Serena covers approximately 295 miles. With FlixBus, this journey generally takes about 5 hours 35 minutes. The quickest coach on this route makes 2 stop(s). FlixBus coaches on this route are equipped with spacious seating, individual power outlets, and onboard toilets. Moreover, complimentary Wi-Fi is standard on most of our coaches. During booking, subject to availability, you have the option to reserve seats such as panoramic, table, or bed seats. Many of our coach services offer coach travel at different times, whether you prefer to travel first thing in the morning or late afternoon and into the evening. Some of our routes even include a night bus to ensure you truly get the most of your time at your destination. Check the rides available from Santiago to La Serena to find the best option according to your schedule. Choosing a coach journey for this route is an environmentally friendly choice, and with FlixBus, passengers have the opportunity to offset their carbon footprint by selecting the CO₂ compensation option at the time of ticket purchase.
In Santiago, there are4 coach stops, namely Santiago (Los Libertadores), Santiago (Pajaritos), Santiago (Terminal Del Sol), Santiago (Terminal San Borja). For La Serena, it features a single stop: La Serena (Bus terminal La Serena). These stops can be located on the map provided on this page.
The first FlixBus service departing from Santiago to La Serena is scheduled for 06:15.
The last FlixBus of the day from Santiago to La Serena is at 23:59.
Travelers journeying from Santiago to La Serena are entitled to one checked bag (dimensions: 50x80x30 cm or 19.7x31.5x11.8 inches, weight: up to 20 kg or 44 lbs) and a carry on bag (dimensions: 30x42x18 cm or 11.8x16.5x7.1 inches, weight: up to 7 kg or 15.4 lbs) free of charge. For specifics on extra or unique baggage, consult our luggage policy. Bikes can be ferried on FlixBus, subject to slot availability. Refer to for more information and our bike pricing guide for rates.
There's no requirement for a printed ticket for your journey between Santiago and La Serena. After completing your online booking, you'll receive an email containing a PDF with a QR code, which serves as your digital ticket. If you booked via the FlixBus App, your ticket will be saved there. Just present this digital QR code to the driver upon boarding.
To keep track of your coach's timely arrival between Santiago and La Serena, use the FlixBus Real-Time Coach Tracker. This tool provides updated information about potential delays.
Child fares for journeys between Santiago and La Serena depend on the child's age and the timing of your booking. Children under 15 benefit from a reduction on the standard adult fare. We automatically apply the best available rate at the time of booking. If a promotional discount exceeds the child fare, that discount will be applied. More information is available in our child travel guidelines. Please note, prams and foldable pushchairs not exceeding a total size of 240 cm (94.5 inches) can be stored in the luggage compartment at no additional charge.
Absolutely. Every FlixBus service operating between Santiago and La Serena caters to passengers with mobility challenges. Our priority is ensuring access and comfort for everyone. Additionally, service animals are welcome on all journeys between these cities. We also accommodate wheelchairs, folding wheelchairs, and other mobility aids at no extra charge.

Searching for coach tickets from Santiago to La Serena?

You're in the right place! Here are all the essentials to organise your coach trip. Travelling from Santiago to La Serena will typically take around 5 hours 35 minutes and can start at a mere £5.99. Coaches set off at 06:15 with the last one departing at 23:59. FlixBus provides 10 services every day between Santiago and La Serena. With FlixBus, benefit from complimentary Wifi, power points, and a reserved seat for your travel.

Steps to secure your coach ticket from Santiago to La Serena

It's straightforward to book with FlixBus. Either on this site or via the free FlixBus App, you can finalise your booking in moments. When buying your ticket from Santiago to La Serena online, we offer multiple secure online payment options, like credit card, Paypal, and even Google and Apple Pay. Or, you can opt for cash on the coach or at an authorised retailer.

Why Opt for FlixBus for Your Journey from Santiago to La Serena?

Uplift your travel game with FlixBus—merging cost-effectiveness with unmatched service. We're eager to have you onboard!

Ample Baggage Provision

Whether you're a light packer or prefer to pack the kitchen sink, we allow one piece of hand luggage and one hold luggage at no extra charge. Want more details? Explore our detailed baggage guidelines.

Journeying with Kids between Santiago and La Serena

We offer reduced rates for youngsters below 15, and pushchairs are brought on free of cost. Dive into our policy for young travellers for further insights.

All-Inclusive Accessibility

Our coach services between Santiago and La Serena are can accommodate passengers with limited mobility. Assistance animals are always welcomed, and we handle the carriage of wheelchairs, collapsible wheelchairs, and other mobility apparatus without any fees.

Facilities Onboard

During your travel between Santiago and La Serena, recline in our roomy seating while enjoyinh free perks such as individual charging points, onboard lavatories, and indeed, complimentary Wi-Fi on most coaches.

Green Travel

Boarding a FlixBus coach nudges you towards a sustainable tomorrow. Tick the CO₂ offset choice during reservation and take comfort in your eco-responsible decision.

Onboard services are subject to availability